Weight Loss News

In the first operations of their kind in Northeastern USA, a bariatric surgery team at Mercy Medical Center in Rockville Centre, New York has performed a unique non-invasive weight loss procedure that uses a new device that reduces the size of a patient’s stomach without the need for any incisions.

Shawn Garber, MD, Chief of Bariatric Surgery at Mercy, is one of the first five surgeons in the United States to learn the StomaphyX(tm) procedure for endoluminal gastric pouch reduction in patients with previous gastric bypass surgery.

The procedure was performed on July 18 on five patients who underwent laparoscopic gastric bypass in 2003 and had been gaining back some weight because of gradual expansion of their gastric pouches. All had their pouches successfully reduced using the new StomaphyX procedure.

“This is an important new option for the 15 to 20 percent of patients who gain weight a few years after undergoing bariatric surgery,” explained Dr. Garber, who heads the New York Bariatric Group. “Because it involves neither abdominal nor internal incisions, this technique is the least invasive, has the lowest risk, and allows patients to recover more quickly and return to their normal activities.”

Dr. Garber and his colleague, Spencer Holover, MD, have performed more than 2,000 weight loss surgeries with the specially-trained team at Mercy, which has been designated as a Bariatric Surgery Center of Excellence by the American Society For Bariatric Surgery.

“This dramatic advance is the future of bariatric surgery,” said Dr. Garber. “The endoluminal technique introduces the instrument that reduces the size of the stomach through the mouth, reducing the risk of infection from surgical incisions, preserving future treatment options, nearly eliminating pain for the patient, and requiring less recovery time than open or even minimally-invasive laparoscopic procedures.”

Acomplia for weight loss

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Acomplia, the new weight-loss pill from Sanofi-Aventis, has not yet been approved in the United States because of questions about its safety. But some Americans have decided not to wait.

Many are traveling to Europe, where the drug has been approved, or buying the medicine through foreign Web sites, while the U.S. Food and Drug Administration continues its evaluations of the treatment. On Monday, a panel of advisers to the agency said that the pill might raise the risk of suicide and suicidal thoughts.

"I don't have very many years to go, and I don't want to spend that time over 200 pounds," said Yvette Cardozo, a 62-year-old American photographer who bought six months' worth of Acomplia during a trip to London. "This is the only thing that's ever worked for me."

Twenty milligrams of Acomplia, the highest dose, resulted in statistically and clinically significant weight loss, the Food and Drug Administration's staff said in documents posted Monday on the agency's Web site. The agency advisory panel will meet Wednesday to discuss whether the medicine's benefits of reducing weight, cholesterol and blood sugar outweigh its risks.

Since clinical tests have shown that the drug can cause anxiety and depression, analysts said the panel might be cautious about approving it without seeing more studies.

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Obese, postmenopausal age women who decide to trim down don't need to worry that they will put themselves in danger of disability by doing so, even if they don't exercise as recommended, a new study shows.

After losing a substantial amount of weight through diet, but without exercising, 23 obese women in their 50s showed no reduction in muscle strength or fitness, even though they had lost muscle mass, Dr. Jamehl Demons of the Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina.

"There was a trend actually toward increasing physical fitness," Demons told Reuters Health. "Our supposition is really that that was due to the weight loss itself."

People lose muscle mass as they age, and some experts have been concerned that weight loss late in life may accelerate muscle loss and increase the risk of disability.

To investigate, Demons and her team had 23 obese women eat 400 calories less per day for five months. They lost an average of 11.6 kilograms (about 26 pounds), 35 percent of which was lean mass or muscle. After the weight loss, the women showed no change in their walking speed or muscle strength. Their aerobic fitness and speed in rising from a chair had improved, although the change wasn't statistically significant.

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Participating in some moderate to vigorous physical activity and limiting TV were key to successful weight loss in teens, according to a U.S. study.

A University of Minnesota Medical School study, published in Obesity, identified common factors among the 16-to-18-year-olds who lost weight including:

-- Females who lost weight averaged 7.6 hours of physical activity a week, and males 11.7 a week.

-- Females were more likely to participate in weight training and strengthening exercises.

-- Teens who lost weight spent significantly less time in front of the television compared to those who gained weight.

Kerri Boutelle, lead author and assistant professor in the department of pediatrics at the University of Minnesota Medical School, says it is clear that exercising, staying active and limiting sedentary activity is essential to teens losing weight.

Obese women who follow low-carbohydrate diets, such as the Atkins diet, may lose more weight in a four-month period than those who go on low-fat diets, new study findings show. The reason for the greater weight loss, however, is not clear.

"The differential weight loss is not explained by differences in resting energy expenditure, thermic effect of food or physical activity," write study author Dr. Bonnie J. Brehm, of the University of Cincinnati, Ohio and her team.

In a previously published study, Brehm and her colleagues compared the effects of a low-carbohydrate diet versus a low-fat diet among obese women. They found that the women on the low-carbohydrate diet lost more than twice as much weight as those in the comparison group during a six-month study period.

The researchers hypothesized that the greater weight loss among those on the low-carbohydrate diet was due to the women’s greater energy expenditure. "If it’s not calories in, it must be calories out," Brehm told. Some advocates of low-carbohydrate diets say that such diets promote increased energy expenditure, but this claim has not been formally tested, until now.

To investigate, Brehm and her team randomly assigned 50 moderately obese women to a low-carbohydrate diet group or a low-fat diet group. Only the low-fat group was told to restrict their caloric intake. Forty women completed the study.

By the end of the four-month study, women in both groups had lost weight and body fat, the researchers report in this month’s issue of the Journal of Clinical Endocrinology and Metabolism. However, the low-carbohydrate group lost more than 10 percent of their body weight, while the low-fat group lost about 7 percent. Specifically, the low-carbohydrate group lost 9.8 kilograms (21.6 pounds) of weight and 6.2 kilograms (13.7 pounds) of body fat, while the low-fat group lost about 6.1 kilograms (13 pounds) of weight and 3.2 kilograms (7 pounds) of body fat, the report indicates.

To estimate their level of physical activity, women in both groups were fitted with pedometers, which recorded the number of steps they took daily. At the start of the study, both groups of women had similar pedometer readings, and by the end of the study, there were no significant changes, according to Brehm and her team. Resting energy expenditure was also similar between the two groups at the start of the study and remained comparable four months later.

The thermic effect of food (TEF), which comprises up to 10 percent of the amount of energy consumed daily, includes the energy expended during digestion. When the investigators obtained TEF measurements after the women ate breakfasts containing a similar number of calories, they found that those on the low-fat diet expended more energy in a five-hour period.

This suggests that the low-fat meal was absorbed more quickly than the low-carbohydrate meal, the report indicates. Yet, even if the TEF of the low-carbohydrate meal had been underestimated, the researchers "would not have approached the amount of energy needed to account for the greater weight loss in this group," they write.

"These results confirm that short-term weight loss is greater in obese women on a low-carbohydrate diet than in those on a low-fat diet even when reported food intake is similar," according to Brehm and her team. Weight loss by diet pills like acomplia is not a bad solution for treatment of obesity.

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